Newer antiarrhythmic agents for maintaining sinus rhythm in atrial fibrillation: simplicity or complexity?
نویسندگان
چکیده
منابع مشابه
New antiarrhythmic agents for atrial fibrillation.
22.12 (2002). 66. Beatch GN, Shinagawa K, Johnson BD et al. RSD1235 selectively prolongs atrial refractoriness and terminates AF in dogs with electrically remodeled atria. S. World. Congr. Pharmacol. 24, Abstract 21.11 (2002). 67. Cardiome drug effective for heart patients. Cardiome Pharma Corp. Press Release
متن کاملSinus Rhythm and Chronic Atrial Fibrillation
Methods and Results: Atria versus ventricles have lower IK1, resulting in more depolarized resting membrane potential ( 7 mV). We used higher Ito,fast density in atrium, removed Ito,slow, and included an atrial-specific IKur. INCX and INaK densities were reduced in atrial versus ventricular myocytes according to experimental results. SERCA function was altered to reproduce human atrial myocyte ...
متن کاملAtrial fibrillation. Reversion to normal sinus rhythm.
Auricular, or atrial fibrillation, is one of the most common cardiac arrhythmias. The mechanism of diagnosis will not be considered here, but rather the clinical criteria for attempted reversion to normal sinus rhythm. This report is concerned with the chronic type associated with severe organic heart or vascular disease, and in those persons previously considered bad risks. The treatment of at...
متن کامل[Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation. A survey of a Cochrane review].
BACKGROUND Atrial fibrillation (AF) is the most frequent sustained arrhythmia. AF recurs frequently after restoration of normal sinus rhythm. Antiarrhythmic drugs have been widely used to prevent recurrence, but the effect of these drugs on mortality and other clinical outcomes is unclear. OBJECTIVES To determine, in patients who recovered sinus rhythm after AF, the effect of long-term treatm...
متن کاملThe effect of ranolazine on maintaining sinus rhythm in patients with resistant atrial fibrillation
BACKGROUND Atrial fibrillation (AF) may arise out of anomalous impulse activity at atrial venous junctions. Triggered activity may be a source of abnormal impulse activity. Ranolazine is an anti-anginal agent, which inhibits normal and abnormal late Na+ channel current in the ventricle and peak Na+ channel current in the atrium. This produces an energy sparing effect and stabilizes cardiac memb...
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ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2007
ISSN: 1554-2815,1520-1554
DOI: 10.1093/eurheartj/sum049